Opportunity Information: Apply for RFA CE 22 004

The Research Grants to Prevent Firearm-Related Violence and Injuries (R01) opportunity (Funding Opportunity Number RFA CE 22 004) is a discretionary grant program run by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), specifically the National Center for Injury Prevention and Control (NCIPC), also known as the Injury Center. The program is designed to fund investigator-initiated research that deepens understanding of firearm-related harms and, more importantly, identifies and tests practical ways to prevent them. The CDC frames the problem broadly, treating firearm-related injuries, deaths, and crime as a public health issue that spans multiple settings and populations, and the purpose of the grant is to build evidence that can guide real-world prevention strategies.

The scope of firearm-related outcomes covered by this announcement is intentionally wide. It includes mass shooting incidents, firearm homicides and assaults that are not mass shootings, firearm suicides and self-harm, unintentional firearm deaths and injuries, and firearm-related crime. In other words, the program is not limited to one type of event or one type of intervention context. A project could focus on preventing suicide and self-harm, reducing community firearm assaults, improving safety to reduce unintentional injuries, or examining approaches that reduce firearm-related crime, as long as the research goal is aligned with understanding prevention and generating evidence that can be used to improve safety.

The central intent is twofold. First, CDC wants research that can inform the development of innovative and promising opportunities to enhance safety and prevent firearm-related injuries, deaths, and crime. Second, CDC also wants rigorous evaluation of innovative and promising strategies that are already being tried or proposed, with the goal of determining how well they work, for whom they work, and under what conditions. The emphasis on rigor signals that proposals should be designed to produce credible, actionable findings rather than purely descriptive work. The practical end point CDC highlights is keeping individuals, families, schools, and communities safer, which implies interest in interventions and strategies that can be implemented in real settings and potentially scaled or adapted.

In terms of eligibility, the opportunity is very open. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (as long as they are not institutions of higher education in that category); for-profit organizations other than small businesses; small businesses; and other entity types as allowed under the announcement language. This broad eligibility means projects can be led by universities, public agencies, nonprofits, tribal entities, or private-sector research organizations, which can be important for partnering with communities and institutions where prevention strategies are being implemented.

The award information provided indicates an award ceiling of $650,000 and an expectation of about 25 awards. The activity category is Health, and the program is associated with CFDA number 93.136. The notice shows a creation date of November 8, 2021, with an original closing date of February 4, 2022, and it specifies that electronic applications were due by 5:00 PM Eastern Time on the listed due date. Taken together, those details describe a competitive federal research grant opportunity aimed at producing prevention-focused evidence on firearm-related violence and injury, with funding levels intended to support substantial research and evaluation efforts and enough awards to build a portfolio of studies across different firearm-related outcomes and settings.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Research Grants to Prevent Firearm-Related Violence and Injuries (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
  • This funding opportunity was created on Nov 08, 2021.
  • Applicants must submit their applications by Feb 04, 2022 Electronically submitted applications must be submitted no later than 500 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $650,000.00 in funding.
  • The number of recipients for this funding is limited to 25 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)

What is this grant opportunity called?

The opportunity is titled "Research Grants to Prevent Firearm-Related Violence and Injuries (R01)." The Funding Opportunity Number is RFA CE 22 004.

Which federal agency runs this program?

This is a discretionary grant program under the U.S. Department of Health and Human Services (HHS), administered through the Centers for Disease Control and Prevention (CDC).

Which CDC center is responsible for this funding?

The program is run by CDC's National Center for Injury Prevention and Control (NCIPC), also known as the Injury Center.

What is the main purpose of the program?

The program funds investigator-initiated research that increases understanding of firearm-related harms and, importantly, identifies and tests practical ways to prevent firearm-related injuries, deaths, and crime.

How does CDC frame the issue in this announcement?

CDC frames firearm-related injuries, deaths, and crime as a public health issue that spans multiple settings and populations, with an emphasis on generating evidence that can guide real-world prevention strategies.

What kinds of firearm-related outcomes are within scope?

The scope is broad and includes mass shooting incidents; firearm homicides and assaults that are not mass shootings; firearm suicides and self-harm; unintentional firearm deaths and injuries; and firearm-related crime.

Is the funding limited to mass shootings?

No. Mass shooting incidents are included, but the announcement explicitly covers many other firearm-related outcomes, including non-mass-shooting homicides and assaults, suicide and self-harm, unintentional injuries, and firearm-related crime.

Can a project focus on suicide and self-harm prevention?

Yes. Firearm suicides and self-harm are specifically listed among the outcomes covered by the announcement.

Can a project focus on unintentional firearm injuries?

Yes. Unintentional firearm deaths and injuries are explicitly included in the scope.

Can a project address firearm-related crime?

Yes. Firearm-related crime is included as an outcome area within the announcement's scope.

What types of research does CDC want to fund?

CDC describes two main priorities: (1) research that can inform development of innovative and promising opportunities to enhance safety and prevent firearm-related harms, and (2) rigorous evaluation of innovative and promising strategies that are being tried or proposed, to determine how well they work, for whom, and under what conditions.

Does this program emphasize evaluation?

Yes. The announcement highlights rigorous evaluation of innovative and promising strategies, with the goal of producing credible, actionable findings.

Is purely descriptive research the focus of this funding?

The emphasis is on producing credible, actionable findings that inform prevention and evaluate strategies. The announcement stresses rigor and practical usefulness rather than being framed as purely descriptive work.

What is the practical end goal CDC highlights?

The practical endpoint described is improving safety for individuals, families, schools, and communities by building evidence that can guide real-world prevention strategies.

Who is eligible to apply?

Eligibility is broad and includes state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (with or without 501(c)(3) status, as long as they are not institutions of higher education in that category); for-profit organizations other than small businesses; small businesses; and other entity types as allowed under the announcement language.

Are institutions of higher education eligible?

Yes. Both public/state-controlled institutions of higher education and private institutions of higher education are listed as eligible applicants.

Can nonprofit organizations apply?

Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status are listed as eligible, with the noted condition that this category is not for institutions of higher education.

Can tribal entities apply?

Yes. Federally recognized Native American tribal governments and other tribal organizations are included as eligible applicants.

Can for-profit organizations apply?

Yes. For-profit organizations other than small businesses are eligible, and small businesses are also listed as eligible.

Can local governments and school districts apply?

Yes. State, county, and city or township governments are eligible, as are independent school districts and special district governments.

What is the award ceiling listed for this opportunity?

The award ceiling shown is $650,000.

How many awards does CDC expect to make?

The announcement indicates an expectation of about 25 awards.

What is the activity category for this opportunity?

The activity category is Health.

What CFDA number is associated with this program?

The program is associated with CFDA number 93.136.

What are the key dates shown in the notice?

The notice shows a creation date of November 8, 2021, and an original closing date of February 4, 2022.

When were applications due, and how were they submitted?

The notice specifies that electronic applications were due by 5:00 PM Eastern Time on the listed due date.

What does "investigator-initiated research" mean in this context?

Based on the announcement language, the program supports research proposed and led by applicants (rather than only pre-defined projects), as long as the work aligns with CDC's prevention-focused goals for firearm-related harms.

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