Opportunity Information: Apply for RFA FD 21 023
The National Food and Nutrient Analysis Program (NFNAP) cooperative agreement opportunity (RFA FD 21 023) is a discretionary funding announcement from the U.S. Department of Health and Human Services, Food and Drug Administration (FDA), specifically within the Center for Food Safety and Applied Nutrition (CFSAN). The purpose is to continue and strengthen NFNAP through a new FDA-led cooperative agreement after the program was previously administered through the U.S. Department of Agriculture (USDA), within the Methods and Application of Food Composition Laboratory (MAFCL), with support from FDA and other federal partners. The overall aim is practical and data-driven: to maintain and expand a validated nutrient database that can be relied on by scientists, government agencies, and other stakeholders who need accurate composition data to monitor diets, evaluate nutrient intake, and support nutrition-related research and policy.
At the core of the program is the routine updating of food composition information for traditional nutrients while also expanding coverage for bioactive compounds that are gaining scientific attention. Traditional nutrients include the kinds of components commonly tracked in nutrition surveillance and labeling contexts, while bioactive compounds can include phytochemicals and other constituents that may influence health but are not always part of standard nutrient panels. The grant emphasizes that NFNAP does not just compile numbers from the literature; it generates high-quality analytical data by sampling foods and dietary supplement units and then testing them using modern, state-of-the-art laboratory methods. A major priority is rigorous quality control throughout analysis and data review so the resulting values are defensible and consistent enough to be used broadly for scientific and regulatory purposes.
Another key focus is understanding and documenting nutrient variability in specific foods. Nutrient levels can change due to differences in agricultural practices, geography, seasonality, processing, formulation changes, and other real-world factors. NFNAP supports research designed to characterize that variability, which helps database users interpret nutrient values more realistically and improves the reliability of intake estimates when those values are used in dietary surveys and exposure assessments. In addition, the program supports the development and validation of new analytical methods when existing procedures are not sufficient, especially for emerging phytochemicals or other food constituents where standardized methods may be limited or still evolving.
From an administrative standpoint, the funding mechanism is a cooperative agreement (U01), meaning FDA is expected to have substantial involvement in the project compared with a standard grant. The activity category aligns with agriculture, consumer protection, and food and nutrition, and the assistance listing is under CFDA 93.103. The opportunity anticipated a single award, with an award ceiling of $300,000. The original posting date was January 8, 2021, and the original application deadline was March 9, 2021. Eligibility is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)," indicating that applicants likely needed to review the full eligibility language in the complete announcement to confirm whether their organization type and capabilities fit FDA expectations.
In practical terms, the award is meant to sustain a national-level capability for generating and curating analytically verified nutrient and bioactive compound data for foods and dietary supplements. The end product is not only updated database entries, but also improved methods and better understanding of how and why nutrient values vary, which collectively supports nutrition monitoring, public health research, and evidence-based decision-making. Clinical trials are explicitly not applicable for this funding opportunity, reflecting that the work centers on analytical chemistry, sampling, data quality systems, and database support rather than human intervention studies.Apply for RFA FD 21 023
- The Department of Health and Human Services, Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "National Food and Nutrient Analysis Program (U01) Clinical Trial Not Applicable" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
- This funding opportunity was created on Jan 08, 2021.
- Applicants must submit their applications by Mar 09, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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